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pentobarbital will minimize the extent or outcome of quetiapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will minimize the level or outcome of irinotecan liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will decrease the extent or impact of rolapitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Extended-phrase coadministration of potent CYP3A4 inducers with rolapitant may appreciably decrease rolapitant efficacy.
pentobarbital will lower the level or effect of gefitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the extent or influence of etoposide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the extent or impact of stiripentol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. If unable to avoid coadministration of stiripentol with solid CYP3A4 inducers, raise stiripentol dose.
Phenobarbital has been shown to shorten the 50 %-life of doxycycline for so long as two weeks just after barbiturate therapy is discontinued. This mechanism is most likely throughout the induction of hepatic microsomal enzymes that metabolize the antibiotic.
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pentobarbital will reduce the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Take into consideration an increase in cannabidiol dosage (depending on clinical response and tolerability) when coadministered with a solid CYP3A4 inducer.
pentobarbital will lower the extent or outcome of tamoxifen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will reduce the extent or effect of linagliptin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Use of alternative treatment options is strongly advised when linagliptin is always to be administered that has a CYP3A4 inducer
pentobarbital will boost the degree or effect of check here clopidogrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will lessen the level or impact of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. The efficacy of hormonal contraceptives could possibly be lessened. Use of a nonhormonal contraceptive is recommended.